Invasive ductal carcinoma of the breast

Case contributed by Bhavna Batohi
Diagnosis almost certain

Presentation

Screening mammogram

Patient Data

Age: 50 years
Gender: Female

Screening mammogram

mammography
MLO
CC
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There is extremely dense fibroglandular tissue (BI-RADS D).

There is a small ill-defined mass in the right upper inner quadrant in the retroglandular space, anterior to the pectoral muscle. On the CC view, the mass is seen in the medial breast and, therefore, falls in two of the forbidden zones on mammography.

This is best regarded as an M4 lesion and should be recalled for assessment.

Right breast

ultrasound
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An irregular mass is seen in the right upper inner quadrant. This causes posterior acoustic shadowing and interruption of the fat planes (U5).

The axillary lymph nodes were normal, with a thin cortex and preserved hilum (not shown).

Post-wire localisation

mammography
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A wire was inserted to localise the mass for surgical excision. These mammograms show good placement of the tip of the wire at the site of the tumour.

Case Discussion

There are four forbidden zones on mammography:

  • anterior to the pectoral muscle (milky way)

  • behind the nipple

  • retroglandular space

  • medial breast

Lesions that fall within these regions should be regarded as suspicious for cancer as there is less glandular breast tissue in these locations. This is particularly so if the lesion is new in comparison to the previous screening mammogram.

The lesion was confirmed to be a grade 2 invasive ductal carcinoma at surgical excision.

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