Kallmann syndrome

Case contributed by A.Prof Frank Gaillard


History withheld.

Patient Data

Age: 16 years
Gender: Female

MRI brain (single image)

Single coronal T2 image through the frontal lobes demonstrates abnormal anatomy with absence of the olfactory bulbs and olfactory sulcus. The gyrus rectus and medial orbital gyrus form a single gyrus. 

Annotated image

Annotated images

It is easiest to appreciate the anatomical anomalies present in Kallman syndrome by comparing it to a normal patient. The normal anatomy of the region consists of the olfactory bulbs (blue arrows) located in the olfactory grooves of the anterior cranial fossa. The inferior surface of the frontal lobes usually consists gyrus rectus (aka straight gyrus) (R) separated from the medial orbital gyrus (M) by the olfactory sulcus (yellow arrow). These are absent in Kallman syndrome. 

Case Discussion

Kallmann syndrome is rare, but has characteristic imaging findings which should be sought in patients with delayed onset of puberty / hypogonadism. 

PlayAdd to Share

Case information

rID: 6083
Case created: 19th Apr 2009
Last edited: 15th Nov 2015
Inclusion in quiz mode: Included

Updating… Please wait.

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.