Non-keratinizing nasopharyngeal carcinoma

Case contributed by Frank Gaillard
Diagnosis almost certain


2-month history of increased nasal congestion and headache with associated increased hyponasal voice.

Patient Data

Age: 60 years
Gender: Male

Contrast enhanced CT of the neck demonstrates a very large heterogeneously enhancing mass of the nasopharynx extending into and through the clivus and down to the C1 anterior arch / dens.

Case Discussion

The patient went on to have a nasopharyngeal biopsy which demonstrated invasive non-keratinizing squamous cell carcinoma.

It is staggering how large some base of skull tumors can become before coming to clinical attention.

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