Presentation
History of prematurity, presented with a developmental delay.
Patient Data
Age: 2 years
Gender: Female
From the case:
Periventricular leukomalacia - end stage
![](https://prod-images-static.radiopaedia.org/images/55114465/MR0013_thumb.jpeg)
![This study is a stack](/packs/stack-YQKLCKBI.gif)
![](https://prod-images-static.radiopaedia.org/images/55114489/MR0013_thumb.jpeg)
![This study is a stack](/packs/stack-YQKLCKBI.gif)
![](https://prod-images-static.radiopaedia.org/images/55114513/MR0013_thumb.jpeg)
![This study is a stack](/packs/stack-YQKLCKBI.gif)
![](https://prod-images-static.radiopaedia.org/images/55114441/MR0013_thumb.jpeg)
![This study is a stack](/packs/stack-YQKLCKBI.gif)
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![](https://prod-images-static.radiopaedia.org/images/55114465/MR0013_big_gallery.jpeg)
The MRI sequences demonstrate:
ventriculomegaly with irregular margins of the bodies and trigones of the lateral ventricles
loss of periventricular white matter with increased signal on FLAIR and T2 sequences
thinning of the corpus callosum
Case Discussion
MRI features most consistent with end-stage periventricular leukomalacia (PVL).