Thymoma and myasthenia gravis

Case contributed by Shervin Sharifkashani , 25 Mar 2022
Diagnosis almost certain
Changed by Yaïr Glick, 29 Mar 2022

Updates to Case Attributes

Presentation was changed:
History of eyelid ptosis and chest pain and. Known myasthenia gravis.
Body was changed:

The concurrence of myasthenia gravis, eyelid ptosis, and thymoma is relatively common and mediastinum imaging is important in the evaluation of ptosis cases. The main differential diagnosis of anterior mediastinal masses is thymoma and germ cell tumors. Biopsy was done and a non. Non-invasive thymoma was reported by the pathologist. MRI and MDCT are both practical for thymoma staging and follow-up.

The concurrence of myasthenia gravis, eyelid ptosis, and thymoma is relatively common, which is why imaging the mediastinum is important in the evaluation of ptosis cases. The main differential diagnosis of anterior mediastinal masses is thymoma and germ cell tumours.

  • -<p>The concurrence of <a href="/articles/myasthenia-gra">myasthenia gravis</a>, eyelid <a href="/articles/ptosis">ptosis</a>, and <a href="/articles/who-classification-scheme-for-thymic-epithelial-tumours-1">thymoma </a>is relatively common and mediastinum imaging is important in the evaluation of ptosis cases. The main differential diagnosis of <a href="/articles/differential-for-an-anterosuperior-mediastinal-mass">anterior mediastinal</a> masses is thymoma and <a href="/articles/anterior-mediastinal-germ-cell-tumours">germ cell t</a>umors. Biopsy was done and a non-invasive thymoma was reported by the pathologist. MRI and MDCT are both practical for thymoma staging and follow-up.</p>
  • +<p>Biopsy was done. Non-invasive thymoma was reported by the pathologist. MRI and MDCT are both practical for thymoma staging and follow-up.</p><p>The concurrence of <a href="/articles/myasthenia-gra">myasthenia gravis</a>, eyelid <a href="/articles/ptosis">ptosis</a>, and <a href="/articles/who-classification-scheme-for-thymic-epithelial-tumours-1">thymoma </a>is relatively common, which is why imaging the mediastinum is important in the evaluation of ptosis cases. The main differential diagnosis of <a href="/articles/differential-for-an-anterosuperior-mediastinal-mass">anterior mediastinal</a> masses is thymoma and <a href="/articles/anterior-mediastinal-germ-cell-tumours">germ cell tumours</a>.</p>

References changed:

  • 1. De Rosa A, Fornili M, Maestri Tassoni M et al. Thymoma‐associated Myasthenia Gravis : Clinical Features and Predictive Value of Antiacetylcholine Receptor Antibodies in the Risk of Recurrence of Thymoma. Thorac Cancer. 2020;12(1):106-13. <a href="https://doi.org/10.1111/1759-7714.13724">doi:10.1111/1759-7714.13724</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/33142021">Pubmed</a>
  • 2. Strange C, Ahuja J, Shroff G, Truong M, Marom E. Imaging Evaluation of Thymoma and Thymic Carcinoma. Front Oncol. 2021;11:810419. <a href="https://doi.org/10.3389/fonc.2021.810419">doi:10.3389/fonc.2021.810419</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/35047412">Pubmed</a>
  • De Rosa A, Fornili M, Maestri Tassoni M et al. Thymoma‐associated Myasthenia Gravis : Clinical Features and Predictive Value of Antiacetylcholine Receptor Antibodies in the Risk of Recurrence of Thymoma. Thorac Cancer. 2020;12(1):106-13. <a href="https://doi.org/10.1111/1759-7714.13724">doi:10.1111/1759-7714.13724</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/33142021">Pubmed</a>
  • Strange C, Ahuja J, Shroff G, Truong M, Marom E. Imaging Evaluation of Thymoma and Thymic Carcinoma. Front Oncol. 2021;11:810419. <a href="https://doi.org/10.3389/fonc.2021.810419">doi:10.3389/fonc.2021.810419</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/35047412">Pubmed</a>

Systems changed:

  • Chest

Updates to Study Attributes

Findings was changed:

There is a well-defined solid mass lesion in the anterior superior mediastinum prevascular region and no. No obvious or gross mediastinal lymph nodes.

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