Known case of diffuse large B cell lymphoma, received multiple lines of chemotherapy. Diffuse large B-cell lymphoma is the most common form of non-Hodgkin lymphoma.

The small bowel is the second most common area to be involved in gastrointestinal lymphoma (after the stomach), where the ileum is the most site for recurrence.

The differential diagnosis is small bowel adenocarcinoma, it shows more surrounding fat planes, less bulky lymph nodes and is associated with intestinal obstruction.

Also another differential diagnosis gastrointestinal stromal tumor, it is not associated with lymphadenopathy.