This patient had a history of an ulcer on the left foot that progressively increased in size and was diagnosed as nodular melanoma based on histopathological results. This type represents approximately 15% of melanomas. It often appears quickly as a bump on the skin. It is usually black but can be pink or red.

Melanoma is the third most common cause of brain metastases, after lung cancer and breast. It can affect the brain and leptomeninges. In 75% of cases, metastatic lesions are multiple.