Choroid plexitis

Last revised by Frank Gaillard on 16 Oct 2024

Choroid plexitis is a general term referring to an inflammatory process affecting the choroid plexus; it is usually due to an infectious process. It is rarely seen as an isolated process and is commonly found in association with encephalitis, meningitis, or ventriculitis 1

The choroid plexus can also be a place of noninfectious inflammatory disorders, such as granulomatosis with polyangiitis, sarcoidosis, xanthogranulomas, and rheumatoid nodules 2,3.

Pathology

The choroid plexus lies at the interface between the cerebrospinal fluid and the systemic circulation, its capillaries have a fenestrated epithelium that serves as a way through which infectious organisms may gain access to the CNS 1,2

Radiographic features  

CT and MRI

Often, the imaging manifestations are dominated by other locations of infection and/or inflammation. Involvement of the choroid plexus leads to 1-4:

  • enlargement (symmetric or asymmetric)

  • increased or asymmetric enhancement

  • adjacent subependymal edema

  • adjacent ependymal enhancement

Cases and figures

  • Case 1: granulomatous disease
  • Case 2: tuberculous meningitis
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