Diabetes insipidus

Last revised by Ashesh Ishwarlal Ranchod on 23 Dec 2023

Diabetes insipidus is the deficiency or resistance to the hormone vasopressin (antidiuretic hormone), which results in polyuria and polydipsia. 

Diabetes insipidus occurs in 3 per 100,000 people 2

Diabetes insipidus may be described as 1-3:

  • central/neurogenic/hypothalamic: vasopressin deficient (more common)
  • peripheral/nephrogenic: vasopressin resistant

Desmopressin can be used to treat central diabetes insipidus 4

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