Endocrine venous sampling

Dr Bruno Di Muzio et al.

Endocrine venous sampling is a set of similar interventional techniques proposed for the specific diagnosis of some endocrine disorders such as: 

  • inferior petrosal sinus sampling
  • selective venous sampling for primary hyperparathyroidism
    • preoperative localization of functioning parathyroid adenoma which cannot be localized by imaging
  • arterial stimulation and selective venous sampling for pancreatic endocrine tumors
    • used for preoperative localization of pancreatic endocrine tumors (gastrinoma, insulinoma, VIPoma, glucagonoma, somatostatinoma and pancreatic polypeptide-producing tumor)
  • adrenal venous sampling
    • used for identification of primary aldosteronism (Conn syndrome or bilateral idiopathic adrenal hyperplasia). 
  • ovarian venous sampling
    • used to stablish the source of excessive androgen production in women when imaging studies are not revealing 3

Renal vein sampling (renin sampling) was used for the determination of renal artery stenosis as cause of hypertension (renovascular hypertension), now infrequently performed 1

Article information

rID: 25493
Synonyms or Alternate Spellings:
  • Endocrine venous samplings

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Cases and figures

  • Case 1: adrenal vein sampling
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