Facial clefts comprise of a wide spectrum of pathologies which result from failure of fusion in the facial region during the embryonic - early fetal period. This results is gap in the fetal face. These clefts can affect the lip, philtrum, alveolus and hard and soft palate to varying degrees.
Entities that fall under this group include
Overall there is a broad spectrum of severity ranging from minimal defects (e.g bifid uvula) to large deep clefts involving both bone and soft tissues.
The estimated incidence of isolated facial clefts may be as high as 1 in 1000 births 1.
There are several classification systems for facial clefts
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