Citation, DOI, disclosures and article data
Citation:
Bell D, Hyperpyrexia. Reference article, Radiopaedia.org (Accessed on 17 Feb 2025) https://doi.org/10.53347/rID-75079
Hyperpyrexia, also known as hyperthermia, is a term reserved for very high fevers and is usually only deemed to be present when the core body temperature is >41.5°C 1,2.
Clinical presentation
Very high fevers appear to be markedly deleterious for cognitive wellbeing, patients often being delirious and mentally impaired with coma rapidly intervening in most cases without aggressive resuscitation.
Differential diagnosis
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1. Krishnan S, Nigam P, Bachh O, Vasudevan M. Quad Fever: Treatment Through Lowering of Ambient Temperature. Indian J Crit Care Med. 2018;22(1):43-5. doi:10.4103/ijccm.IJCCM_295_17 - Pubmed
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2. Sterkel S, Akinyemi A, Sanchez-Gonzalez M, Michel G. Preserving Brain Function in a Comatose Patient with Septic Hyperpyrexia (41.6 °C): A Case Report. J Med Case Rep. 2017;11(1):40. doi:10.1186/s13256-017-1204-8 - Pubmed
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