Idiopathic hypereosinophilic syndrome

Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder and refers to a situation when there is an unexplained prolonged eosinophilia with associated organ system dysfunction. The condition can affect several organ systems which includes:

Individuals have prolonged raised total leukocyte counts with raised eosinophil counts. Usually the total leukocyte counts are less than 25,000/μL with 30-70% comprising of eosinophils. At times extremely high leukocyte counts  (>90,000/μL) can also develop which can then result in a poorer prognosis.

Radiographic features are probably best discussed under individual categories.

It was first described by W R Hardy and R E Anderson in 1968 4.

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Article information

rID: 19557
Synonyms or Alternate Spellings:
  • Idiopathic hypereosinophilic syndrome (iHES)
  • Idiopathic hypereosinophilic syndrome (HES)
  • Idiopathic hypereosinophilic syndrome (IHS)

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