Lateral pontine syndrome
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At the time the article was created Ahmed Abdrabou had no recorded disclosures.
View Ahmed Abdrabou's current disclosuresAt the time the article was last revised Rohit Sharma had no financial relationships to ineligible companies to disclose.
View Rohit Sharma's current disclosures- Marie-Foix syndrome
- Lateral pontine stroke syndrome
- Marie-Foix-Alajouanine syndrome
Lateral pontine syndrome, also known as Marie-Foix syndrome or Marie-Foix-Alajouanine syndrome, refers to one of the brainstem stroke syndromes of the lateral aspect of the pons.
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Clinical presentation
There is a characteristic clinical presentation 1,2,4:
-
ipsilateral
limb ataxia: cerebellar tracts
loss of pain and temperature sensation of the face: spinal trigeminal tract and nucleus
facial weakness: facial nerve (CN VII)
hearing loss, vertigo and nystagmus: vestibulocochlear nerve (CN VIII)
-
contralateral
loss of pain and temperature sensation: spinothalamic tracts
Pathology
The lateral pontine syndrome occurs due to occlusion of perforating branches of the basilar and anterior inferior cerebellar (AICA) arteries 1,2.
History and etymology
The syndrome was first described by Pierre Marie (1853-1940), Charles Foix (1882-1927), and Théophile Alajouanine (1890-1980), French neurologists, in 1922 3.
References
- 1. Kumral E, Bayülkem G, Evyapan D. Clinical Spectrum of Pontine Infarction. Clinical-MRI Correlations. J Neurol. 2002;249(12):1659-70. doi:10.1007/s00415-002-0879-x - Pubmed
- 2. Nouh A, Remke J, Ruland S. Ischemic Posterior Circulation Stroke: A Review of Anatomy, Clinical Presentations, Diagnosis, and Current Management. Front Neurol. 2014;5:30. doi:10.3389/fneur.2014.00030 - Pubmed
- 3. Marie P, Foix C, Alajouanine T. De I'atrophie cerebelleuse tardive a predominance corticale. Rev Neurol (Paris). 1922;29:1082-111.
- 4. Balami J, Chen R, Buchan A. Stroke Syndromes and Clinical Management. QJM. 2013;106(7):607-15. doi:10.1093/qjmed/hct057 - Pubmed
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