Lethal omphalocele-cleft palate syndrome
Prevalence is assumed to be <1 per 1,000,000. It has been postulated that this syndrome is likely to be an autosomal recessive condition 1.
History and etymology
Czeizel described this syndrome for the first time in three daughters born of normal non-consanguineous parents 1.
- 1. Czeizel A. New lethal omphalocele-cleft palate syndrome?. Hum. Genet. 1983;64 (1): 99. Pubmed citation
- 2. Sharma D, Murki S, Pratap T. A newborn with omphalocele and umbilical cord cyst: an interesting entity. Iranian journal of pediatrics. 24 (4): 449-50. Pubmed
- 3. Agarwal R. Prenatal diagnosis of anterior abdominal wall defects: Pictorial essay. Indian Journal of Radiology and Imaging. 15 (3): 361. doi:10.4103/0971-3026.29157