Liquefactive necrosis

Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass.


In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist of fluid with remains of necrotic tissue or pus.


It is commonly associated with infection, dependant on the site of involvement.


Reported organs include:

  • lung
    • a lung abscess if considered a form of liquefactive necrosis
  • brain 3
  • spleen 2
  • pancreas 1
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Article information

rID: 53996
Section: Pathology
Synonyms or Alternate Spellings:
  • Colliquative necrosis

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