Liquefactive necrosis

Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass.

Pathology

In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist fluid with remains of necrotic tissue or pus. 

Associations

It can commonly be associated with infection dependant on the site of involvement

Location

Reported organs include

  • lung
    • a lung abscess if considered a form of liquefactive necrosis
  • brain 3
  • spleen 2
  • pancreas 1
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Article information

rID: 53996
Section: Pathology
Synonyms or Alternate Spellings:
  • Colliquative necrosis

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