Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass.
In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist of fluid with remains of necrotic tissue or pus.
It is commonly associated with infection, dependant on the site of involvement.
Reported organs include:
- a lung abscess if considered a form of liquefactive necrosis
- brain 3
- spleen 2
- pancreas 1
- 1. Burrell M, Gold JA, Simeone J, Taylor K, Dobbins J. Liquefactive necrosis of the pancreas: the pancreatic sac. Radiology. 135 (1): 157-60. doi:10.1148/radiology.135.1.7360954 - Pubmed
- 2. Downer WR, Peterson MS. Massive splenic infarction and liquefactive necrosis complicating polycythemia vera. AJR. American journal of roentgenology. 161 (1): 79-80. doi:10.2214/ajr.161.1.8517327 - Pubmed
- 3. Estes ML, Rorke LB. Liquefactive necrosis in Coxsackie B encephalitis. Archives of pathology & laboratory medicine. 110 (11): 1090-2. Pubmed