Neonatal encephalopathy is a clinical syndrome referring to signs and symptoms of abnormal neurological function in the first few days of life in a neonate born at or beyond 35 weeks of gestation. It is described as difficulty with initiating and maintaining respiration, depression of tone and reflexes, subnormal level of consciousness, and often by seizures.
It may result from a variety of conditions and the most common is global hypoxic-ischemic brain injury.
- 1. Edwards AD, Nelson KB. Neonatal encephalopathies. Time to reconsider the cause of encephalopathies. BMJ. 1999;317 (7172): 1537-8. Free text at pubmed - Pubmed citation
- 2. Adamson SJ, Alessandri LM, Badawi N et-al. Predictors of neonatal encephalopathy in full-term infants. BMJ. 1995;311 (7005): 598-602. doi:10.1136/bmj.311.7005.598 - Free text at pubmed - Pubmed citation
- 3. Chao CP, Zaleski CG, Patton AC. Neonatal hypoxic-ischemic encephalopathy: multimodality imaging findings. Radiographics. 2006;26 Suppl 1 (suppl_1): S159-72. doi:10.1148/rg.26si065504 - Pubmed citation