Neuronal nuclear antigen (NeuN)

Last revised by Frank Gaillard on 23 Aug 2023

Neuronal nuclear antigen (NeuN) is a protein expressed in mature (post-mitotic) neurons and is commonly used as an immunohistochemical target to identify neuronal differentiation (e.g. in ganglioglioma and gangliocytomas).

It is primarily expressed in the nuclei of neurons with less pronounced expression in the cytoplasm and dendrites and axons 1.

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