Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Yap J, Luong D, et al. Nodular bronchiectatic mycobacterium avium complex pulmonary disease. Reference article, Radiopaedia.org (Accessed on 06 Mar 2025) https://doi.org/10.53347/rID-54868
Nodular bronchiectatic mycobacterium avium complex pulmonary disease is a morphological form of pulmonary mycobacterium avium complex infection although it is worthwhile understanding that there can be a spectrum of the disease with mixed forms.
This form may have a greater predilection in postmenopausal women.
Location
Although non-specific, there is a tendency towards the right middle lobe and lingular division of the left upper lobe 2.
Treatment and prognosis
In the nodular form, lung parenchymal abnormalities have been shown to demonstrate a significant decrease in extent on imaging following antibiotic treatment (usually macrolide-containing regimens), mainly related to the improvement of cellular bronchiolitis.
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1. Lee G, Lee KS, Moon JW, Koh WJ, Jeong BH, Jeong YJ, Kim HJ, Woo S. Nodular bronchiectatic Mycobacterium avium complex pulmonary disease. Natural course on serial computed tomographic scans. Annals of the American Thoracic Society. 10 (4): 299-306. doi:10.1513/AnnalsATS.201303-062OC - Pubmed
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2. Lee G, Kim HS, Lee KS, Koh WJ, Jeon K, Jeong BH, Ahn J. Serial CT findings of nodular bronchiectatic Mycobacterium avium complex pulmonary disease with antibiotic treatment. AJR. American journal of roentgenology. 201 (4): 764-72. doi:10.2214/AJR.12.9897 - Pubmed
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3. Jeong BH, Jeon K, Park HY, Kim SY, Lee KS, Huh HJ, Ki CS, Lee NY, Shin SJ, Daley CL, Koh WJ. Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. American journal of respiratory and critical care medicine. 191 (1): 96-103. doi:10.1164/rccm.201408-1545OC - Pubmed
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4. Wallace RJ, Brown-Elliott BA, McNulty S, Philley JV, Killingley J, Wilson RW, York DS, Shepherd S, Griffith DE. Macrolide/Azalide therapy for nodular/bronchiectatic mycobacterium avium complex lung disease. Chest. 146 (2): 276-282. doi:10.1378/chest.13-2538 - Pubmed
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5. Song JW, Koh WJ, Lee KS, Lee JY, Chung MJ, Kim TS, Kwon OJ. High-resolution CT findings of Mycobacterium avium-intracellulare complex pulmonary disease: correlation with pulmonary function test results. AJR. American journal of roentgenology. 191 (4): 1070. doi:10.2214/AJR.07.3505 - Pubmed
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