Pancreatic neoplasms

Last revised by Joshua Yap on 24 Jan 2023

There are numerous primary pancreatic neoplasms, in part due to the mixed endocrine and exocrine components.

Classification

Classification based on function
Exocrine tumors

See also: cystic pancreatic mass: differential diagnosis

Endocrine tumors

Endocrine tumors of the pancreas are divided into:

  • functional: ~85%

  • non-functional: ~15%

    • third most common

    • 85-100% malignant

    • usually larger, as a result of lack of hormonal activity, the clinical presentations are usually delayed till they become large

Mesenchymal tumors

Account for 1-2% of all pancreatic tumors and are classified according to their histologic origin 7. These are further discussed in pancreatic mesenchymal neoplasms.

Classification based on location 
Head
Body and tail
Intraductal

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Cases and figures

  • Figure 1: gross pathology - pancreatic carcinoma
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  • Case 1
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  • Case 2: insulinoma
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  • Case 3: insulinoma
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  • Case 4: neuroendocrine tumor
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  • Case 5: pancreatic ductal adenocarcinoma
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  • Case 6
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  • Case 7: neuroendocrine tumor and serous cystadenoma
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  • Case 8: metastatic pancreatic adenocarcinoma
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