Primary serous papillary carcinoma of the peritoneum

A primary serous papillary carcinoma of the peritoneum (PSPCP) is an extremely rare primary peritoneal tumour.

They usually present in postmenopausal women.

Patients tend to present with non-specific complaints such as abdominal pain, anorexia, and abdominal distention.

It is histologically identical to serous papillary carcinoma of the ovary 7. PSPCP is believed to originate from either peritoneal mesothelial cells with müllerian differentiation or nests of ovarian tissue remnants within the peritoneum

Markers

Serum CA-125 levels may be elevated 3-4.

CT

While most features are nonspecific, CT features of diffuse peritoneal, omental and mesenterial involvement especially in middle-aged or elderly postmenopausal women with normal-size ovaries in the absence of an identifiable primary site in and conjunction with elevated level of serum CA-125 may suggest the possibility of PSPCP 6.

On imaging, a PSPCP can resemble that of peritoneal carcinomatosis 

Other considerations include

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Article information

rID: 13591
Tag: cases
Synonyms or Alternate Spellings:
  • Primary serous papillary carcinoma of the peritoneum (PSPCP)
  • Primary peritoneal serous papillary carcinoma
  • Primary peritoneal serous papillary carcinoma (PPSPC)
  • Primary peritoneal papillary serous adenocarcinoma

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