Spinal epidural haematoma

Last revised by Tariq Walizai on 17 Dec 2024

Spinal epidural haematomas are rare and can result in severe morbidity if treatment is delayed and they are thus typically considered a surgical emergency. 

The patient's symptoms and signs will depend on the location of the haematoma, and the degree of spinal cord/cauda equina compression. Typically there will be a combination of severe pain and neurological deficit. See spinal cord injury and cauda equina syndrome for more information. 

Spinal epidural haematomas are most commonly spontaneous venous bleeds, often in the setting of coagulopathy or over-anticoagulation. They are anatomically located in the space between the theca and the periosteum - known as the extradural neural axis compartment.

  • spontaneous: most common 4

    • especially in the context of a bleeding disorder or over-anticoagulation

  • trauma, e.g. vertebral fracture

  • iatrogenic, e.g. lumbar puncture, epidural anaesthesia

  • spinal arteriovenous malformations or other vascular anomalies

  • spinal tumours

  • pregnancy

Spinal epidural haematomas can occur throughout the spine but are most common in the cervicothoracic region, usually posterior to the thecal sac over 2-4 vertebral levels 1,4.

  • non-contrast: hyperdense (50-70 HU) extradural mass 4

Signal characteristics will vary on the age of the blood. Signal characteristics of acute spinal epidural haematomas 1,2,5:

  • T1: isointense or hyperintense to spinal cord

  • T2: heterogeneously hyperintense to spinal cord with hypointense foci

  • SWI/T2*: blooming artifact

Cases and figures

  • Case 1: T2
  • Case 2: T1 C+ fat sat
  • Case 3: non-contrast CT
  • Case 4: T2
  • Case 5
  • Case 6: thoracic and lumbar spine
  • Case 7: on CT due to chalkstick fracture in ankylosing spondylitis
  • Case 8

Imaging differential diagnosis

  • Spinal subdural haematoma - inverted Mercedes-Benz sign
  • Epidural lipomatosis
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