Subcutaneous rheumatoid nodules
Subcutaneous rheumatoid nodules are the most common extra-articular manifestation of rheumatoid arthritis (RA), occuring in up to 40% of patients. They are universally associated with a positive rheumatoid factor (RF)1.
The size of the nodules varies from 2 mm to 5 cm; they are firm, nontender, and moveable in subcutaneous tissue2.
- 1. Rheumatoid arthritis: a review of the cutaneous manifestations. Sayah A1, English JC 3rd. J Am Acad Dermatol. 2005 Aug;53(2):191-209; quiz 210-2.
- 2. Rheumatoid nodule. García-Patos V1. Semin Cutan Med Surg. 2007 Jun;26(2):100-7.