Usual interstitial pneumonia (American thoracic society criteria for histopathological diagnosis)

Dr Amir Rezaee et al.

American Thoracic Society (ATS) criteria for histopathological diagnosis of usual interstitial pneumonia​ (UIP) are as follows: 

  • advanced subpleural or paraseptal fibrosis +/- honeycombing 
  • patchy temporally heterogeneous fibrosis
  • fibroblastic foci
  • absence of features against UIP
    • inflammatory cells
    • granulomas
    • organising pneumonia

The most important difference is that presence of honeycombing is not a major criteria for diagnosis of UIP in pathology as opposed to chest HRCT, although in majority of cases microscopic fibrotic cysts can be seen which could be considered precursors of the macroscopic subpleural honeycombing on HRCT chest. 

Share article

Article Information

rID: 45288
System: Chest
Section: Pathology
Synonyms or Alternate Spellings:
  • ATS criteria for diagnosis of UIP on pathology
  • American Thoracic Society (ATS) critera for histopathological diagnosis of usual interstitial pneumonia​ (UIP)
  • American Thoracic Society criteria for histopathological diagnosis of usual interstitial pneumonia

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.