Extensive hypoxic-ischemic insult

Case contributed by Dalia Ibrahim
Diagnosis almost certain

Presentation

Presented to ER with hypoglycemic coma. Arrested twice.

Patient Data

Age: 25 years
Gender: Female
This study is a stack
Axial
non-contrast
This study is a stack
Axial bone
window
This study is a stack
Sagittal
non-contrast
This study is a stack
Coronal
non-contrast
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Info

Diffuse cerebral edema and low attenuation with loss of grey-white matter interface, compression of the lateral ventricles and effacement of the cerebral cisterns and extra-axial CSF spaces. The cerebellum is spared (white cerebellum sign). Also, there's cerebellar tonsil herniation.

Case Discussion

In this case, CT demonstrates extensive ischemic damage (e.g.cerebral edema, reversal sign, and herniation), which are suggestive of brain death. However, only CT/MRI angiography is recognized as a potential alternative to angiography and nuclear medicine studies in diagnosis of brain death.

CT angiography relies upon the non-opacification of intracranial vessels.

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