Hypertensive microangiopathy

Case contributed by Ammar Haouimi
Diagnosis almost certain

Presentation

Cognitive impairment in a patient with poorly controlled hypertension.

Patient Data

Age: 55 years
Gender: Female
mri
This study is a stack
Coronal
T1
This study is a stack
Axial
FLAIR
This study is a stack
Axial
T2
This study is a stack
Coronal
T2
This study is a stack
Axial
Gradient Echo
This study is a stack
Axial
DWI
This study is a stack
Axial
ADC
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Info

Extensive high FLAIR and T2 changes through the supratentorial periventricular white matter in keeping with chronic small vessel ischemia. Old lacunar infarcts are seen at the supratentorial white matter and in the pons with ex vacuo ventriculomegaly.

Multiple punctate areas of susceptibility signal loss are seen on gradient echo mainly in the basal ganglia.

Case Discussion

MRI features are most consistent with hypertensive microangiopathy also called chronic hypertensive encephalopathy.

On imaging the main differential diagnosis is cerebral amyloid angiopathy which usually has a peripheral distribution, and tends to spare the basal ganglia and pons.

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