Hippocampal sclerosis

Case contributed by Elena Filimonova
Diagnosis certain

Presentation

Long-standing pharmacoresistant complex partial temporal lobe epilepsy

Patient Data

Age: 35 years
Gender: Female
mri
This study is a stack
Coronal
oblique T2
This study is a stack
Axial
oblique T2
This study is a stack
Coronal
FLAIR
This study is a stack
Axial
T1
This study is a stack
Axial
T2
This study is a stack
Axial
DWI
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Info

There is hippocampal asymmetry (right smaller than the left). The right hippocampus demonstrates T2/FLAIR hyperintensity with loss of internal architecture. In addition, there is a slight asymmetry of mammillary bodies (right smaller than the left). Features are consistent with right side mesial temporal sclerosis (or hippocampal sclerosis).

Case Discussion

Mesial temporal sclerosis is the most common association with intractable temporal lobe epilepsy. Histologically there is neuronal cell loss, gliosis, and sclerosis.

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