Acute M1 occlusion with ischemic penumbra (CT perfusion)

Case contributed by Craig Hacking
Diagnosis certain

Presentation

Sudden onset right hemiparesis and facial droop. Onset of symptoms 60 min before scan.

Patient Data

Age: 75 years
Gender: Female
This study is a stack
Axial
non-contrast
This study is a stack
Axial non-contrast
thins
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Info

Grey-white matter differentiation is maintained. Hyperdensity in the proximal aspect of the M1 segment of the left MCA. No hemorrhage, mass effect or midline shift. The ventricles and basal cisterns are normal.

This study is a stack
Axial C+ arterial
phase thins
This study is a stack
Axial angiogram
thick MIP
This study is a stack
Axial 10 sec
delay thick MIP
This study is a stack
Axial 16 sec
delay thick MIP
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Info

Filling defect of approximately 4 mm within the M1 segment of the left MCA. Distal vessel flow is preserved. Good collateral flow.

Patent dural venous sinuses.

This study is a stack
MTT
This study is a stack
Tmax
This study is a stack
TTD
This study is a stack
TTP
This study is a stack
CBF
This study is a stack
CBV
This study is a stack
FED
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Info

Large area of increased MTT, TTD and TTP with decreased CBF but preserved CBV in the left MCA territory representing penumbra. Small posterior focus of decreased CBF and decreased CBV representing core infarct.  

Acute left MCA territory cerebral infarction secondary to an occlusive thrombus within the M1 segment of the left MCA. Predominately penumbra within the left MCA territory, with a small proportion of core infarct.

The patient proceeded immediately to the neurointerventional angiographic suite for mechanical thrombectomy.

Mechanical thrombectomy

dsa
This study is a stack
Frontal Pre
ECR ICA
This study is a stack
Lateral Pre
ECR ICA
This study is a stack
Frontal Post
ECR ICA
This study is a stack
Lateral Post
ECR ICA
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Info

Left M1 occlusion. Mechanical thrombectomy performed 120 minutes after onset. Successful first pass, post thrombectomy TICI 3.

Symptoms completely resolved in recovery bay.

Case Discussion

Good example of a M1 occlusion in a slow progressor with good collaterals. The CT perfusion color maps show predominantly penumbra in the left MCA territory.

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