Beta thalassaemia

Case contributed by Dr Ian Bickle

Presentation

Beta thalassemia patient with a fever. Collection?

Patient Data

Age: 22
Gender: Female
CT

CT chest

Small paravertebral soft tissue abnormalities in keeping with extramedullary haematopoiesis.

Lungs clear.

CT abdomen

Hepatomegaly. The liver is diffusely hyperdense.

Multiple tiny low attenuation foci in the liver, likely to represent small abscesses.

Moderate splenomegaly.

Multiple enlarged lymph nodes/necrotic lymph nodes in the upper abdomen, the para-aortic space, small bowel mesentery and left anterior abdomen.

Small gallstones.

Coarse echotexture to the bony skeleton.
 

Case Discussion

Fellowship exam long or viva case example of a thalassemia patient.

Features evident:

  • extramedullary haemopoesis (typical paravertebral location)
  • hyperattenuating liver from repeat blood transfusions given secondary haemochromatosis
  • gallstones
  • hepatosplenomegaly ( or splenectomy or infarcted spleen in other cases)
  • coarse appearance to the bones
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Case information

rID: 48490
Case created: 10th Oct 2016
Last edited: 12th Oct 2016
System: Haematology
Inclusion in quiz mode: Included

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