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Bilateral adrenal granulocytic sarcomas (chloromas)

Case contributed by Dr Michael P Hartung


Abdominal pain, history of CML.

Patient Data

Age: 70 years
Gender: Female

Left larger than right adrenal masses. Porta hepatis adenopathy. 

Case Discussion

Bone marrow biopsy confirmed AML. The adrenal masses were not biopsied separately, but granulocytic sarcoma involving both adrenal glands is a sensible explanation and has been described in this setting, although it is very rare1. A staging PET exam showed elevated uptake involving several muscular/osseous sites poorly seen on this study. The differential diagnosis for such large masses would be lymphoma or adrenocortical carcinoma (which occurs in ~10% of cases of carcinoma). 

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Case information

rID: 78375
Published: 15th Jun 2020
Last edited: 16th Jun 2020
Inclusion in quiz mode: Included

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