Complete pancreatic lipomatosis: cystic fibrosis

Case contributed by Dr Chris O'Donnell


Past medical history of cystic fibrosis. Has had bilateral lung transplant. Now diabetic with abnormal liver function.

Patient Data

Age: 35
Gender: Female

Non-contrast intravenous CT scan, patient also has renal failure

Complete fatty replacement of the pancreas (arrows), i.e. no residual pancreatic parenchyma with marked fatty infiltration of the liver (another common manifestation of CF) and hepatic contour changes indicative of cirrhosis and portal hypertension (also seen in CF).

Case Discussion

There are a number of causes of complete pancreatic lipomatosis:

  • cystic fibrosis (most common cause in childhood)  
  • metabolic/endocrine: hyperlipidemia, diabetes mellitus
  • storage disease: haemochromatosis
  • drugs: steroids
  • infectious: viral infection, sepsis
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Case information

rID: 33034
Case created: 28th Dec 2014
Last edited: 18th May 2017
Inclusion in quiz mode: Included

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