Complete pancreatic lipomatosis: cystic fibrosis

Case contributed by Dr Chris O'Donnell

Presentation

Known cystic fibrosis with bilateral lung transplants. Now diabetic and chronic renal failure with abnormal liver function.

Patient Data

Age: 35 years
Gender: Female
CT

Non-contrast CT scan

Complete fatty replacement of the pancreas (arrows), i.e. no residual pancreatic parenchyma with marked fatty infiltration of the liver (another common manifestation of CF) and hepatic contour changes indicative of cirrhosis and portal hypertension (also seen in CF).

Case Discussion

There are a number of causes of complete pancreatic lipomatosis:

  • cystic fibrosis (most common cause in childhood)  
  • metabolic/endocrine: hyperlipidemia, diabetes mellitus
  • storage disease: haemochromatosis
  • drugs: steroids
  • infectious: viral infection, sepsis
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Case information

rID: 33034
Case created: 28th Dec 2014
Last edited: 9th Sep 2017
Inclusion in quiz mode: Included

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