Endometrioid adenocarcinoma

Case contributed by Dr Morlie L Wang

Presentation

30 yo female presented with right sided abdominal pain. On exam, patient had acute abdomen and mass palpated (26 week size).

Patient Data

Age: 30
Gender: Female
Modality: CT

CT with contrast

Endometroid cystadenofibroma

Case Discussion

Final "expert" pathology of right adnexal mass: endometrioid adenocarcinoma of the ovary, grade I, resembling Sertoli-stromal tumour.  The carcinoma arises in the background of a borderline endometrioid cystadenofibroma. The capsule is free of involvement by carcinoma. The fallopian tube had no specific pathological change.

Note: Originally, it was felt that this tumor represented a Sertoli-Leydig tumor, intermediate type with an endometrioid component. This was favoured over a pure endometrioid carcinoma due to the young age of the patient. However, due to the prominence of an endometrioid component and uncertainty regarding the clinical significance of this finding the case was sent for expert of opinion.

Expert opinion: endometrioid adenocarcinoma resembling Sertoli-stromal cell tumor with well-moderate differentiation. No unequivocal invasion.

Gross description: A portion of the surface of the ovary has a dusty apearance. The rest of the external surface is pinksh to purplish tan and smooth. Sections reveal a largely solid surface wtih multiple cysts. The  largest cyst measures 8 cm and is filled with a large amount of blood clot. Other cysts are filled with hemorrhagic fluid.  A second large cyst also about 8 cm at the opposite pole from the hemorrhagic cyst contains necrotic material. Many of the cysts have a nodular inner lining with foci of papillary projections. 

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Case Information

rID: 13980
Case created: 6th Jun 2011
Last edited: 17th Dec 2015
System: Gynaecology
Inclusion in quiz mode: Included

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