Ewing sarcoma

Case contributed by Fernando Figueredo Savi
Diagnosis certain

Presentation

Patient fractured the left clavicle, four months later a suspicious lesion was found on the control radiograph.

Patient Data

Age: 20 years
Gender: Female
x-ray

The radiograph shows an expansive lesion in the left clavicle with a permeative appearance. Zanca view demonstrates the difference with the normal clavicle.

Nuclear medicine

Scintigraphy shows moderate increased uptake at the humeral end of the left clavicle. No signs of bone metastases are observed.

ct

Osteolytic lesion with irregular edges on the left clavicle extending into the supraspinatus muscles, with a suspicious appearance.

mri

MRI shows a lesion in the left clavicle, with hyposignal on T1, hypersignal on T2, with contrast uptake, compromising the entire distal portion of the left clavicle, acromioclavicular joint, part of the acromion and extending to adjacent soft tissues.

Surgical specimen

x-ray

Radiographs taken after surgical resection. The expansive lesion with a permeative appearance.

Surgical reconstruction

x-ray

After reconstruction.

Case Discussion

The patient suffered a fracture of the left clavicle after a fall from his own height. Four months later, a follow-up X-ray was performed, which revealed an expansile lesion with a permeative appearance, suspicious for neoplasia. Immunohistochemistry showed a pattern compatible with Ewing's sarcoma. Surgical resection was performed after chemotherapy, and histology confirmed the diagnosis.

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