Femoral lymphoma

Case contributed by Craig Hacking
Diagnosis certain

Presentation

One month of worsening left hip pain.

Patient Data

Age: 90 years
Gender: Male
x-ray
Frontal
Lateral
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Permeative lesion with wide zone of transition in the left subtrochanteric femur. Posterior cortical destruction. No pathological fracture evident.

ct
This study is a stack
Axial C+
arterial phase
This study is a stack
Axial bone
window
This study is a stack
Coronal C+
arterial phase
This study is a stack
Coronal
bone window
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Large left pelvic and proximal thigh soft tissue mass encases the proximal femur by more than 180 degrees. Associated cortical erosion is demonstrated with intramedullary tumor extension posteriorly where significant erosion and permeative change is seen, extending to the greater femoral trochanter. Tumor involves the entire femoral medullary cavity over a length of 14.5 cm from the femoral neck. A minimally displaced pathologic intertrochanteric fracture is also noted with horizontal and vertical components, better appreciated on coronal images. No intra-articular extension into the hip joint.

The large soft tissue tumor mass also involves the left obturator externus and internus muscles, with erosion of the left inferior pubic ramus. Tumor is also seen in the mid pelvis, inseparable from the prostate and from a 30 mm tumor nodule in the left ischioanal fossa. Tumor lies clear of the left sciatic nerve.

Normal appearance of the distal femur and proximal tibia.

No abnormality is seen in the sacrum.

No pathologically enlarged inguinal lymph nodes by size criteria.

CONCLUSION:

The pathologically diagnosed B-cell lymphoma displays a large predominantly extra osseous component in the proximal left thigh and pelvic cavity.

Intramedullary left femoral tumor extension is evident with a pathologic intertrochanteric fracture.

MRI could not be performed due to an incompatible pacemaker.

Soft tissue biopsy was performed under US guidance following discussion with the orthopedic oncology MDT.

Histology: high grade B cell lymphoma.

FDG PET/CT showed no disease elsewhere.

x-ray
Frontal
Frontal
Lateral
Lateral
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Info

Prophylactic IMHS of the left femur. No hardware complication. Stable right proximal femoral permeative lesion. No pathological fracture evident.

Case Discussion

The patient was eligible for CTX and palliative RTX and transferred back to a local hospital.

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