Focal hepatic steatosis in primary sclerosing cholangitis

Case contributed by Mohammad Taghi Niknejad
Diagnosis almost certain

Presentation

Abdominal pain.

Patient Data

Age: 60 years
Gender: Female
This study is a stack
Axial
non-contrast
This study is a stack
Axial C+
arterial phase
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Axial C+ portal
venous phase
This study is a stack
Axial C+ portal
venous phase
This study is a stack
Axial C+
delayed
This study is a stack
Axial C+
delayed
This study is a stack
Coronal C+ portal
venous phase
This study is a stack
Sagittal C+ portal
venous phase
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Info

A lobulated geographic hypodense area is seen occupying most of the right lobe and the medial segment of the left lobe with the blood vessels seen transversing this region without interruption. The lesion becomes less distinct in delayed images. No mass effect could be detected.
Mild intrahepatic bile duct dilatation is seen.

This study is a stack
Axial
T2_haste_tra_bh_p2
This study is a stack
Axial
T2_haste_tra_bh_p2_f.s
This study is a stack
Axial
T2+t2_haste_tra_mbh
This study is a stack
Axial
T1_f12d_fs_tra_p2_mbh
This study is a stack
Axial
T1_f12d_in_opp_tra_p2_mbh
This study is a stack
Axial
T1_f12d_in_opp_tra_p2_mbh
This study is a stack
Coronal
T2_haste_cor_bh_p2
This study is a stack
Coronal
T2_hasteirm_cor_mbh_p2
This study is a stack
Sagittal
T2_haste_fs_thick_sl_p2
This study is a stack
Axial
Ep2d_diff_tra_b0_b200_b800_p2_160
This study is a stack
Axial
Ep2d_diff_tra_b0_b200_b800_p2_160_adc
This study is a stack
Coronal
T2_spc_rst_cor_p3_iso_trig_384
This study is a stack
<Mip
range>
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Info

Signal dropout on opposed phase T1W GRE images is noted in the 4th and 8th hepatic segments in favor of fatty infiltration.
Alternating dilated and stenotic segments of the intrahepatic bile ducts are visible.
Mild irregularity of the common bile duct. Low signal filling defect is noted in the gallbladder.
Subtle periportal edema is present.

Case Discussion

Biliary duct changes related to primary sclerosing cholangitis (known case) which is an uncommon inflammatory condition and affects the biliary tree resulting in multiple strictures, liver damage, and eventually cirrhosis.

Patchy focal fat deposition and relative fatty sparing may be mistaken for a focal neoplasm (particular on US and CT) and thus MR in-phase and opposed-phase imaging allows reliable differentiation

 

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