Neurosarcoidosis

Case contributed by Assoc Prof Frank Gaillard

Presentation

Presentation unknown.

Patient Data

Age: 40 years
Gender: Male

MRI brain

MRI

Multiple patchy region of increased T2 signal are demonstrated associated with contrast enhancement. Some of the these are periventricular, some are subcortical and others are in the brainstem. 

MRI brain - 4 years later

MRI

4 years later enhancement persists but has altered in appearance and distribution.

Case Discussion

This patient had systemic sarcoidosis diagnosed on histology from a lung biopsy. Changes are consistent with neurosarcoidosis. The presence of enhancement 4 years later strongly argues against demyelination. 

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