Paget disease - skull

Case contributed by Roberto Schubert
Diagnosis almost certain


CT recommended for severe headaches.

Patient Data

Age: 85 years
Gender: Female

Thickened sclerotic bone, especially at the skull base and large areas of radiolucencies with deformity of the skull vault on the right.

Case Discussion

Paget disease of the bone is a chronic bone disorder characterized by excessive abnormal bone remodeling. 

In the skull, both inner and outer calvarial tables are involved. Osteolysis is frequently seen as well-defined, often large areas of radiolucency most commonly affecting the frontal and occipital bones which referred to as osteoporosis circumscripta.

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