Primary CNS lymphoma

Case contributed by Austin Neuropathology
Diagnosis certain

Presentation

Unsteady gait for three weeks.

Patient Data

Age: 75 years
Gender: Male
ct
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Info

CT demonstrates a periventricular hyperdense lesion.

mri
This study is a stack
Sagittal
T1
This study is a stack
Axial
T2
This study is a stack
Axial
T1
This study is a stack
Axial
DWI
This study is a stack
Axial
ADC
This study is a stack
Axial
FLAIR
This study is a stack
Axial
T1 C+
This study is a stack
Coronal
T1 C+
This study is a stack
Sagittal
T1 C+
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Info

MRI confirms the presence of a periventricular enhancing lesion which demonstrates restricted diffusion and enhancement.

Histology

pathology
H&E
CD20
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Info

Small round blue cells with strong positive immunostain for CD20 (B cell marker), consistent with Non-Hodgkin large B cell lymphoma.

Case Discussion

Features consistent with lymphoma which confirmed on pathology.

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