Presentation
Back pain. Previous history of gynecological cancer, which including radiotherapy treatment.
Patient Data
Age: 60 years
Gender: Female
From the case:
Radiation induced fatty marrow replacement
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Info
High signal on both T1 and T2 in a very demarcated fashion involving L2 to the sacrum.
No focal bone lesion.
Conus and cauda equina normal.
Case Discussion
This example shows fatty replacement of the bone marrow due to radiation therapy. After 3-6 weeks marrow cellularity is replaced by central fat predominantly surrounding the basivertebral veins. Hence on all MRI sequences in the zone of radiation therapy, the bones return signal consistently with fat.
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