Squamous cell carcinoma of the tongue

Case contributed by Dr Bruno Di Muzio


Heavy smoker and alcohol abuse. Ulcerated lesion in the tongue.

Patient Data

Age: 56-year-old
Gender: Male

CT Neck

Enhancing ulcerated lesion within the anterolateral aspect of the tongue on the left. A few small left Ib lymph nodes are non-specific. 


Panoramic radiographic (OPG)

Poor dentition. No suspicious bone lesions. 


Tongue US

Heterogenous hypoechoic nodular lesion involving the anterolateral left aspect of the tongue, measuring 2.9 x 1.9 x 2.7 cm (across x deep x long).

Case Discussion

Punch biopsy of the tongue was performed: 

MICROSCOPIC DESCRIPTION: Sections show stratified squamous mucosa and infiltrating squamous cell carcinoma with cords and nests of cells having keratin pearls and abundant intercellular bridges. There are numerous mitotic figures including atypical forms. The stroma is desmoplastic. There is no lymphovascular or perineural invasion identified. 2. Sections show a fragment of tissue predominantly composed of tumour of similar appearance to that seen in specimen 1 with a little benign, inflamed squamous epithelium at one end.

DIAGNOSIS: 1. Left anterior lateral tongue, biopsy: Squamous cell carcinoma. 2. Punch biopsy left anterior lateral tongue: Squamous cell carcinoma.

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Case information

rID: 48116
Case created: 19th Sep 2016
Last edited: 29th Oct 2016
System: Head & Neck
Tag: rmh
Inclusion in quiz mode: Excluded

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