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Swyer-James syndrome

Case contributed by Dr Michael P Hartung


Elevated D-dimer, palpitations.

Patient Data

Age: 30 years
Gender: Male

Mild bronchial wall thickening of the right lower lobe. Relative hyperlucency involving the majority of the right lower lobe and portions of the right middle lobe, with corresponding diminished size of the pulmonary vessels supplying these hyperlucent segments. Few other ill-defined areas of mosaicism in within the right upper lobe and left lower lobe. 

Case Discussion

Swyer-James syndrome is post infectious obliterative bronchiolitis, usually a result of childhood infection. Commonly (on board examinations), it is described as "unilateral hyperlucent lung."

However, it often does not involve the entire lung, as in this case1. This is because the point of bronchial obstruction is in the small airways (bronchiolitis), not the larger segmental or central bronchi.

There is right lower and middle lobar hyperlucency, with a few scattered areas of mosaicism within the right upper lobe. There is corresponding diminished size of the pulmonary vasculature supplying the right middle and lower lobes. The left lower lobe has a few very faint areas of mosaic attenuation. 

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Case information

rID: 58451
Published: 20th Feb 2018
Last edited: 27th Jul 2020
System: Chest
Inclusion in quiz mode: Included

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