Synchronous renal and colonic carcinomas

Discussion:

Renal cell carcinoma (RCC) is the commonest malignant renal neoplasm. It is associated with multiple other primary neoplasms, like bladder, prostate, breast, colon, lung and non-Hodgkin lymphoma (NHL) which is a well-known factor; however, its concurrent detection with a gastrointestinal neoplasm is unusual but well acknowledged entity 1. The prevalence of synchronous RCC and colonic malignancy is variable and its reported incidence in the literature usually varies between 0.03-0.5% 1. The exact etiopathogenesis of these synchronous malignancies is not yet fully explained. It is postulated that synchronous malignancies affect the tissues having identical embryological roots 1. Multiple synchronous malignancies occur when these tissues are exposed to certain carcinogens or environmental risk factors (alcohol, tobacco, ultraviolet light, pollution, hormonal factors, chemotherapy, & radiation exposure) 1.

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