4D syndrome is a term used to describe a manifestation of syndromic glucagonoma, a type of pancreatic endocrine tumor.
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D: dermatitis 2
- necrolytic migratory erythema - a widespread rash, tending to involve perioral and perigenital regions
- oral rashes (angular stomatitis, cheilitis)
- tend to resolve upon removal of the tumor
- D: mild diabetes mellitus
- D: deep vein thrombosis
- D: depression - may be related to severe chronic dermatosis 2
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