Adrenal lymphoma
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Saber M, Di Muzio B, et al. Adrenal lymphoma. Reference article, Radiopaedia.org (Accessed on 24 Mar 2025) https://doi.org/10.53347/rID-71852
Permalink:
rID:
71852
Article created:
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Revisions:
6 times, by
5 contributors -
see full revision history and disclosures
Systems:
Synonyms:
- Adrenal lymphomas
- Lymphoma of adrenal glands
- Lymphoma involving adrenal glands
- Lymphoma involving adrenals
Adrenal lymphoma can refer to:
- primary adrenal lymphoma: rare
- can be bilateral in around 70% of cases 1
- secondary involvement of the adrenal glands with lymphoma: more common
Clinical presentation
The presentation can be variable and may include adrenal insufficiency, worsening general state, weight loss, and abdominal pain.
Radiographic features
CT/MRI
Maybe seen as bulky adrenal masses. Often difficult to use bilaterality to differentiate primary versus secondary since the former can be bilateral in a considerable portion of cases.
Usually of soft tissue attenuation (40-60 HU) with mild progressive enhancement after contrast medium administration 9.
Nuclear medicine
- often FDG avid 6
References
- 1. Laurent C, Casasnovas O, Martin L, Chauchet A, Ghesquieres H, Aussedat G, Fornecker LM, Bologna S, Borot S, Laurent K, Bouillet B, Verges B, Petit JM. Adrenal lymphoma: presentation, management and prognosis. (2017) QJM : monthly journal of the Association of Physicians. 110 (2): 103-109. doi:10.1093/qjmed/hcw174 - Pubmed
- 2. Ozimek A, Diebold J, Linke R, Heyn J, Hallfeldt K, Mussack T. Bilateral primary adrenal non-Hodgkin's lymphoma and primary adrenocortical carcinoma--review of the literature preoperative differentiation of adrenal tumors. (2008) Endocrine journal. 55 (4): 625-38. doi:10.1507/endocrj.k08e-035 - Pubmed
- 3. Li Y, Sun H, Gao S, Bai R. Primary bilateral adrenal lymphoma: 2 case reports. (2006) Journal of computer assisted tomography. 30 (5): 791-3. doi:10.1097/01.rct.0000216112.15564.0c - Pubmed
- 4. Jacobs BL, Blodgett TM, Monaco SE, Hrebinko RL, Jacobs SA. Adrenal insufficiency as presenting feature of non-Hodgkin lymphoma. (2010) The Canadian journal of urology. 17 (5): 5411-4. Pubmed
- 5. Nishiuchi T, Imachi H, Fujiwara M, Murao K, Onishi H, Kiguchi T, Takimoto H, Kushida Y, Haba R, Ishida T. A case of non-Hodgkin's lymphoma primary arising in both adrenal glands associated with adrenal failure. (2009) Endocrine. 35 (1): 34-7. doi:10.1007/s12020-008-9125-3 - Pubmed
- 6. Santhosh S, Mittal BR, Shankar P, Kashyap R, Bhattacharya A, Singh B, Das A, Bhansali A. (18)F-FDG PET/CT in bilateral primary adrenal T-cell lymphoma. (2011) Hellenic journal of nuclear medicine. 14 (2): 166-7. Pubmed
- 7. Hamid Zargar A, Ahmad Laway B, Alam Bhat K, Shah A, Ahmad M, Aejaz Aziz S, Iftikhar Bashir M, Iqbal Wani A, Hayat Bhat M. Adrenal insufficiency due to primary bilateral adrenal non-Hodgkin's lymphoma. (2004) Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 112 (8): 462-4. doi:10.1055/s-2004-821231 - Pubmed
- 8. Khurana A, Kaur P, Chauhan AK, Kataria SP, Bansal N. Primary Non Hodgkin's Lymphoma of Left Adrenal Gland - A Rare Presentation. (2015) Journal of clinical and diagnostic research : JCDR. 9 (4): XD01-XD03. doi:10.7860/JCDR/2015/8079.5745 - Pubmed
- 9. Guerrisi A, Marin D, Baski M, Guerrisi P, Capozza F, Catalano C. Adrenal lesions: spectrum of imaging findings with emphasis on multi-detector computed tomography and magnetic resonance imaging. (2013) Journal of clinical imaging science. 3: 61. doi:10.4103/2156-7514.124088 - Pubmed
Unable to process the form. Check for errors and try again.