Dr Shu Su and Dr Donna D'Souza et al.

 Angiosarcomas (like haemangiopericytomas and haemangioendotheliomas) are tumours that arise from vascular structures. They are typically difficult to distinguish from one another on imaging alone.

Angiosarcomas, are the most aggressive of the three, frequently having metastases at the time of diagnosis (and therefore carrying an extremely poor prognosis), and often having local recurrences. 


They account for less than 1% of all sarcomas and are more frequently seen in males (M:F = 2:1) except when seen in the setting of post-mastectomy lymphoedema which is clearly more common in women and is known as Stewart-Treves syndrome.


The malignant cells express morphological and functional properties of endothelial cells. The tumours can be multicentric with haemorrhage and necrosis being common.

Location specific lesions
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Article information

rID: 900
System: Vascular
Tag: cases
Synonyms or Alternate Spellings:
  • Angiosarcoma (General)

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    Case 1: pulmonary angiosarcoma
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