Chronic granulomatous disease (pulmonary manifestations)

Pulmonary manifestations of chronic granulomatous disease can be seen approximately 80% of cases of chronic granulomatous disease, which is a disease characterised by multiple bacterial and fungal infections occurring as a result of a defect in the gene that encodes NADPH oxidase.

The most common infectious agents include Aspergillus, Staphylococcus, Burkholderia, Nocardia and Serratia species. 

Radiographic features

CT - HRCT chest

Many features have been described which are variable and nonspecific on their own.

These include 1,3:

Contiguous extension of disease from the lungs to the pleura or chest wall can be reported in up to one-third of patients 3.

 

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Article information

rID: 26093
System: Chest
Tag: cases
Synonyms or Alternate Spellings:
  • Pulmonary manifestations of chronic granulomatous disease
  • Lung manifestations of chronic granulomatous disease
  • Thoracic manifestations of chronic granulomatous disease

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