Cystic degeneration of a leiomyoma

Last revised by Mostafa El-Feky on 3 Apr 2023

Cystic degeneration is an uncommon type of degeneration that a uterine leiomyoma (fibroid) can undergo.

 This type of degeneration is thought to represent ~4% of all types of uterine leiomyoma degeneration.

When the leiomyoma increases in size, the vascular supply to it becomes inadequate and leads to different types of degeneration: hyaline, cystic, myxoid, or red degenerationDystrophic calcification may also occur. Hyalinization is the commonest type of degeneration. Cystic degeneration is an extreme sequel of edema.

May show a hypoechoic or heterogeneous uterine mass with cystic areas.

Fibroids with this type of degeneration may show cystic areas with portions of high T2 signal on MRI 1

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Cases and figures

  • Case 1: ultrasound
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  • Case 1: CT
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  • Case 2
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  • Case 3
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  • Case 4
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