Cystic endometrial atrophy

Dr Vincent Tatco and Radswiki et al.

Cystic endometrial atrophy is a benign process that can occur as part of Tamoxifen associated endometrial changes

Pathology

It is diagnosed histologically when multiple cystic spaces (dilated glands) lined with atrophic epithelium are present within a dense fibrous stroma. 

At hysteroscopy, the endometrium appears white but hypervascularized, with scattered protuberances. This “tamoxifen-like” mucosa can be seen as early as 6 months after the start of tamoxifen therapy. At histopathologic examination, these protuberances are identified as cystic glandular dilatation 

Differential diagnosis

In certain situations, the changes of endometrial cystic atrophy can be so extensive that the appearance of a cystic endometrium may be mistaken for diffuse or focal areas of endometrial thickening (e.g.  endometrial polyp or endometrial hyperplasia) This may even occur at hysterosonography.

Share article

Article information

rID: 15250
System: Gynaecology
Synonyms or Alternate Spellings:
  • Endometrial cystic atrophy

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.