Diffuse uterine leiomyomatosis

Diffuse uterine leiomyomatosis is a benign and extremely rare condition in which the uterus is symmetrically enlarged as a result of the almost complete replacement of the myometrium by innumerable poorly defined, confluent leiomyomatous nodules. 

Initial symptoms of the diffuse uterine leiomyomatosis usually are abdominal pain and abnormal uterine bleeding. Similar to uterine leiomyomas, patients with leiomyomatosis can present with menorrhagia, dysmenorrhea, abdominal pain, infertility, and pelvic pressure.

The exact aetiology of these neoplasms is incompletely understood. 

MRI
  • is the method of choice
  • the uterus appears diffusely enlarged shoiwng multiple innumerable ill defined leiomyomas without discrete margins
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Article information

rID: 15068
System: Gynaecology
Tag: cases
Synonyms or Alternate Spellings:
  • Uterine leiomyomatosis
  • Leiomyomatosis of the uterus

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