End-stage renal disease

Last revised by Daniel J Bell on 25 Sep 2024

End-stage renal disease, also known as end-stage renal failure or end-stage kidney disease, corresponds to the last stage of chronic kidney disease (stage 5), when the kidneys' function is no longer sufficient to sustain life (eGFR <15 mL/min/1.73m2) and kidney replacement therapy (dialysis or transplant) is required.

Please, refer to the article on chronic kidney disease (CKD) article for a broader discussion on this entity.

Cases and figures

  • Case 1: hyperdense kidneys
  • Case 2: due to autosomal dominant polycystic kidney disease
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